Structural and functional characterisation of the methionine adenosyltransferase from Thermococcus kodakarensis
نویسندگان
چکیده
منابع مشابه
Thermococcus kodakarensis DNA replication.
DNA replication plays an essential role in all life forms. Research on archaeal DNA replication began approximately 20 years ago. Progress was hindered, however, by the lack of genetic tools to supplement the biochemical and structural studies. This has changed, however, and genetic approaches are now available for several archaeal species. One of these organisms is the thermophilic euryarchaeo...
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15 صفحه اولRefolding and characterization of methionine adenosyltransferase from Euglena gracilis.
Methionine adenosyltransferase from Euglena gracilis (MATX) is a recently discovered member of the MAT family of proteins that synthesize S-adenosylmethionine. Heterologous overexpression of MATX in Escherichia coli rendered the protein mostly in inclusion bodies under all conditions tested. Therefore, a refolding and purification procedure from these aggregates was developed to characterize th...
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ژورنال
عنوان ژورنال: BMC Structural Biology
سال: 2013
ISSN: 1472-6807
DOI: 10.1186/1472-6807-13-22